What is the primary use of reserpine in medicine?

Reserpine is primarily used in medicine for managing hypertension, which refers to high blood pressure. Its mechanism of action involves depleting catecholamines, which are neurotransmitters that play a key role in regulating blood pressure. By reducing the levels of these neurotransmitters, reserpine helps to relax blood vessels, thereby lowering blood pressure and alleviating the workload on the heart.

This medication was historically significant as one of the first antihypertensives and reflects an understanding of neurotransmitter mechanisms in cardiovascular health. While reserpine can have various effects on mood and behavior due to its actions on neurotransmitter levels, its primary and most recognized use is in the management of high blood pressure.