What is a potential risk of long-term use of Kava?

Long-term use of Kava is primarily associated with the risk of liver damage. Kava, derived from the roots of the Kava plant (Piper methysticum), is commonly used for its anxiolytic and sedative effects. However, concerns have emerged regarding its hepatotoxic potential.

Studies have indicated that prolonged consumption of Kava can lead to serious liver conditions, including hepatitis, liver failure, and even the need for liver transplantation in severe cases. The exact mechanism of Kava's liver toxicity is still being studied, but it is believed that certain compounds in Kava can lead to oxidative stress and liver enzyme alterations.

It's important for users to be aware of this risk, particularly if they are using Kava improperly or in higher-than-recommended doses, or if they have pre-existing liver conditions, as these factors can exacerbate the potential for liver damage. Regular monitoring and consultation with healthcare providers are advised for those considering long-term use of Kava for its therapeutic benefits.