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Colchicum autumnale, commonly known as autumn crocus or meadow saffron, is notably used for its effective treatment of gout. Gout is a form of arthritis characterized by sudden, severe attacks of pain, swelling, and redness, often affecting the big toe. The active compound in Colchicum autumnale, colchicine, has been used historically to reduce inflammation and alleviate the painful symptoms associated with gout attacks. It works by decreasing the buildup of uric acid crystals in the joints, which are responsible for the painful inflammatory response.

While other options pertain to uses of various plants or medicines within different contexts, they do not relate specifically to Colchicum autumnale. For instance, treating fever and coughs often involves other herbal remedies or pharmaceuticals more suited to those symptoms, and preventing blood clots typically involves anticoagulants rather than colchicine. Therefore, the specific therapeutic application of Colchicum autumnale in the management of gout makes it the correct answer in this context.